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Techniques
In vivo as well as in vitro preparations, along
with a broad array of techniques, are utilized in support of our
research. Current techniques include: cortical
and brainstem slice physiology; intracellular recording; in
vivo multisite extracellular recording; juxtacellular recording; intracortical electrical and optical microstimulation;
in vivo two-photon scanning microscopy to image cell calcium dynamics
and blood flow dynamics; optically-guided in vivo recording;
ultrashort laser
pulses for in
vivo perturbation of cells and tissue; ultrashort laser
pulses for surgery; viral expression techniques; conditioned learning in rodents; histology and immunochemistry;
construction of G-protein receptor-based
reporters (CNiFERs); automatd spike sorting; analytical and numerical methods for data analysis
and modeling.
Funding
We are grateful for generous past and continuing support from
government and philanthropic sources. These include the National
Institutes of Health (NIA, NIBIB, NIDA, NIMH, NINDS, NCRR, NIDCD),
the National Science Foundation (DBI, IBN, IGERT, Physics), the
David and Lucille Packard Foundation, the Human Frontiers Scientific
Program, the Whitehall Foundation, the US-Israeli Binational Science
Foundation, and the Benign Essential Blepharospasm Research Foundation.
Students, fellows, and project scientists in the laboratory
have received direct support from the American Heart Association, Canadian Institute of Health
Research, the Howard Hughes Medical Institute, the National Science
Foundation, the Human Frontiers Scientific Program, and the National
Institutes of Health (NIMH, NSRA). |
